Questions and Answers for Medical Students- Pharmacology- 4

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Q- A 35-year-old woman presents with weight gain, fatigue, and constipation. She is diagnosed with hypothyroidism and started on levothyroxine. Which of the following mechanisms best describes the action of this drug?

A- Blocks TSH secretion

B- Inhibits thyroid peroxidase

C- Replaces deficient thyroid hormone

D- Stimulates iodine uptake

C- Replaces deficient thyroid hormone- Levothyroxine is synthetic T₄, which is converted to active T₃ in peripheral tissues, restoring normal metabolism and thyroid function.

 

Q- Which of the following antibiotics inhibits bacterial protein synthesis by binding to the 50S ribosomal subunit?

A- Ciprofloxacin

B- Clindamycin

C- Doxycycline

D- Gentamicin

B- Clindamycin- Clindamycin binds to the 50S ribosomal subunit, blocking peptide bond formation. It is active against anaerobes above the diaphragm.

 

Q- A patient on long-term corticosteroid therapy suddenly stops the medication. Which of the following complications is most likely to occur?

A- Adrenal crisis

B- Cushingoid appearance

C- Hyperglycemia

D- Hypertension

A- Adrenal crisis- Sudden withdrawal of corticosteroids after long-term use suppresses the hypothalamic-pituitary-adrenal (HPA) axis, leading to acute adrenal insufficiency.

 

Read this book: Pharmacology MCQs for Medical and Pharmacy Students 

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