Questions and Answers for Medical Students- Pathology- 3

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Q- A 67-year-old woman presents with fatigue and bone pain. Serum protein electrophoresis reveals an M spike. A bone marrow biopsy shows: >10% plasma cells.

Which additional finding is most likely revealed in this patient?

A- Auer rods

B- Bence Jones proteins in urine

C- Hypersegmented neutrophils

D- Reed-Sternberg cells

B- Bence Jones proteins in urine- This is a case of multiple myeloma. It is associated with nonclonal plasma cell proliferation and the presence of Bence Jones proteins (light-chain proteins) in the urine.

 

Q- A patient develops acute pancreatitis. Which enzyme is primarily responsible for the autodigestion of pancreatic tissue?

A- Amylase

B- Elastase

C- Lipase

D- Trypsin

D- Trypsin- Premature activation of trypsin triggers activation of other digestive enzymes, which leads to autodigestion.

 

Q- A mutation causes decreased function of CFTR channels. Which ion transport abnormality is expected in sweat glands?

A- Decreased chloride reabsorption

B- Increased chloride reabsorption

C- Increased sodium secretion

D- Increased potassium reabsorption

A- Decreased chloride reabsorption – In cases of cystic fibrosis, a CFTR defect results in impaired Chloride reabsorption, leading to high sweat chloride levels.

 

Read this Pathology MCQs Book

Read this Review Book for Step 1

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