Questions and Answers for Medical Students- Pathology- 1

by

Q- A 24-year-old woman complains of arthralgias and chest pain for 2 years. Chest examination reveals friction rub and dullness to percussion on the back. A chest x-ray shows bilateral pleural effusions.

What is the next step to start workup on this patient?

A- Antinuclear antibody test

B- CD4 lymphocyte count

C- Erythrocyte sedimentation rate

D- Sputum culture

A-Antinuclear antibody test- This is the most appropriate test to start with and if it’s positive, specific tests for auto-immune diseases should follow.

 

Q- A 36-year-old man underwent an abdominal surgery 3 months ago. He develops a small nodule on the skin at the incision site which was sutured during surgery. There is no fever, pain or redness.

What is the reason for developing this nodule?

A- Acute inflammation

B- Antigen-antibody reaction

C- Dermoid cyst

D- Foreign body reaction

D- Foreign body reaction- Foreign material such as sutures can lead to accumulation of macrophages (giant cells) resulting in this reaction.

 

Q- Which one of the following findings is most likely seen in a patient diagnosed with colon adenocarcinoma?

A- Detection of HIV- RNA

B- DNA topoisomerase 1 antibody

C- K-RAS mutation in neoplastic cells

D- Neoplastic cells positive for vimentin

C- K-RAS mutation in neoplastic cells- This mutation is associated with many human carcinomas specially colon cancer.

 

More Pathology Questions

Check this Review Book for USMLE Step 1 

Leave a Comment